Transcriptome Analysis of Mycobacteria in Serum Exosomes of Latent Tuberculosis Patients For Candidate Biomarker Identification

Currently, with the increasing risk of latent tuberculosis (LTB) reactivation, we are expanding our knowledge to study the gene expression of Mycobacterium tuberculosis in serum extracellular vesicles of LTB individuals. The study is an initiative to identify the emerging LTB individuals to prevent the progression to active tuberculosis. This extra effort will entail a substantial financial burden for a country like Sri Lanka unless immediate actions are taken for better diagnosis.